The ICG has gained its research reputation via Cardio-related disease however, to be successful in science collaboration is key. As such, we are also involved with other Institutes that are focused on neurological disease.
Due to this, I had the pleasure to attend a talk by Prof. Dr. Hyder Jinnah from Emory University, USA entitled: “Genotype-Phenotype correlations in movement disorders”.
He discussed with examples, of the three main types of Genotype-Phenotype relationships:
1. From a genotype is linked to a phenotype (one-to-one relationship)
2. Pleiotropy, where from a genotype you can find many phenotypes (one -to- many relationship)
3. Genetic heterogeneity where from a variety of genotypes you can find similar phenotypes (many-to-“one”)
To end Prof. Jinnah discussed the clinical relevance of the different Genotype-Phenotype relationships and downstream options when selecting diagnostics tests.
Due to this, I had the pleasure to attend a talk by Prof. Dr. Hyder Jinnah from Emory University, USA entitled: “Genotype-Phenotype correlations in movement disorders”.
He discussed with examples, of the three main types of Genotype-Phenotype relationships:
1. From a genotype is linked to a phenotype (one-to-one relationship)
2. Pleiotropy, where from a genotype you can find many phenotypes (one -to- many relationship)
3. Genetic heterogeneity where from a variety of genotypes you can find similar phenotypes (many-to-“one”)
To end Prof. Jinnah discussed the clinical relevance of the different Genotype-Phenotype relationships and downstream options when selecting diagnostics tests.
LMV
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