In an international effort we identified 6 further loci associated with CAD.
The paper (open access) is online here.
Background: Novel genetic loci influence risk of coronary artery disease, but only one-third are associated with conventional cardiovascular risk factors, whereas at least one-half of the loci are associated with other diseases or traits (pleiotropy). Future studies should investigate the mechanisms that relate the observed pleiotropy to the pathogenesis of atherosclerosis and ischemic events.
It is always great to see the reward after years of work, phone conferences, discussions, writing, discussions, ...
Link to the German press release.
JE
The paper (open access) is online here.
Background: Novel genetic loci influence risk of coronary artery disease, but only one-third are associated with conventional cardiovascular risk factors, whereas at least one-half of the loci are associated with other diseases or traits (pleiotropy). Future studies should investigate the mechanisms that relate the observed pleiotropy to the pathogenesis of atherosclerosis and ischemic events.
It is always great to see the reward after years of work, phone conferences, discussions, writing, discussions, ...
Link to the German press release.
JE
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